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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a76d8419f4a57f5f089ce7840ec487997581ade64d3d195840c7b6b9a9fe9407' 
  AND token = 'Qgb6/nfFqwawQ9pcRTaiY2Av5VQ9tCtbfzsfFErtSH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}