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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a791189da131479edcdd28da168b6d396d4423f7a03139a6c92a753f564ab449' 
  AND token = 'SbRgmShn8RLTMtE1p56F80sCx33zDwxD3RJYbTeeXCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}