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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '05ffb4c3bfbeaff1853cfceeeeefbef17b7b4050f7eeb43e458cad41809c1f05' 
  AND token = 'c5w/mC3YZp+VEgFgjCY7CSCYMgZGO+9qdKVwvXORUy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}