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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '345c05c401460da1d9debd426df40038fc5157f1169d0868724d794e0216d2a7' 
  AND token = 'xjD+hN4EhVIfZR+MYeb1SfP11STir2DlGeEfIp+L9uQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}