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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '67502beef51192326064664c647120fb212c242e76c16bcb49e562ccab5e0516' 
  AND token = 'iAHgpg+lZf9It18WsRTD6ikDOEUKsdL5bZRW8Ckpxc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}