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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '44e7aa64476111311a2723b520e050521437fee04bea6bd695ecc0752d34c2a5' 
  AND token = 'tdq+EFYOA/FalXE/Tx/lEuuUogcRTrR3wBhuMtHcjGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}