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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5f43b94137ff5be64c062e34151830c59c18f279b523faeb77d94d7b76f14959' 
  AND token = 'zh3EF4phghX+DhWXeR+ntVs33GibEhhucJbVx/rax2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}