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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '65f9c4ce3d51e437d24f65be6d4afa757cfd3f296b2010930733af459a317752' 
  AND token = 'Gb5dyW4uhgxvKG3CMYd7/uPc2RapDGPQmhW1kHs1dcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}