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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1a0c48297412840208538a553b76e6b559299cde8fb51750ad33d836a037da43' 
  AND token = '2sVX2Xgk6SZdDPExc+iSO5ab09g80GMN6zsiBTBHBP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}