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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5546248aa69930398c4a3918f1e4da92b6d3d5f89a10bd6ece7916790592f278' 
  AND token = 'mJOa+EVyGJEGavNhPvp9I4eNrLfhDRbTNcYBv5Jf9iU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}