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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3f023e4856077685427c08b5611eb2a24171e6369c202f46d4e0215eca441d8a' 
  AND token = 'CEedlbalFA4ZSmSQ1SM76B3c5jYrfYlp8OSar3oJ5WA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}