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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'be3b4c6a5a8384c93a120362b2efe14ec57fba5d19d136aa202684abf4fc996b' 
  AND token = 'I3EXzbH1FWWei1pVwrlN/O/fKvHDW9YkE1+s4Yn1Hfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}