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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fc427ada5fb9decb9265ec5185594b012fccbb0f1dfb8294788cb61927b824e0' 
  AND token = '1HqeOWjcIMQf1uQeuqbs7eeY7wbjG7t2VPpggjDMgCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}