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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '66e2902f8d01d331d2161359ba2e1a02068fe761ed8f6ab290ed90eb4679cb2b' 
  AND token = 'ipVmmN4EoFShTjN8yhGG9fnB7vaf1UNMNwVCA0hCSxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}