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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22ade2ea47fa320a1d4bb7dc3f53199d72bac98e60b43d4091b256f5af741472' 
  AND token = 'sT50G8NdK7zMrNseLFX6WfgkQny3beGEkZgPOAse/wI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}