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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1e6839673be50e3ffd1aebd7f87d14e97e79e6a61fd463e68d518004b58fc58f' 
  AND token = 'sAstLmPOcFad3gxYEKPWD10pO0mkc539M/VbtvZOSVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}