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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '74a51e4702d4d2d54910fa2b36088b2c3b79b12820fb01e0ee91ed6079c1c271' 
  AND token = '2yiFEtJ7SwxO8leFSvzSjDHEgmt3iv/XoJcG1OHwN50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}