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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '80f2cc7a78d83f039333379269b06eef44935ffbf84d06a4a5beaf8e45906226' 
  AND token = 'wwGPziGF8GtXjPy1yrW5+RIdijtEIaIGp577FsJU6Es=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}