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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3e0fcb321ec12637e36491ebb9d70503d06bc3ffd04fde11b30df33a3aec811e' 
  AND token = 'h0g/XfCFn6pkq84rz/xBvWKfxyd+A9eIXFv/I0M3nVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}