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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '80562176e69c6fe20700e909c817243feb102a9b3f33621db506220fa8819535' 
  AND token = '1E4pE8mbMeNPAIe50Ibj0qB256PhiU9xVf9iTbDTZhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}