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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '101280f9e13548a3ac976e2b160fed5afa162d9effb2a77abf32f03c9fc899f1' 
  AND token = 'tjaRzuV9SdwYaZgEjSR+8/AAqa6SHzPLrCjO22AyuuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}