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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0d7be8f2a1fbd3233b96879e60f2de046e653295d9d9492d238d02aa065adbf1' 
  AND token = 'NwZRLbdtUum64ObrYAk7HM83pJ2ZOe3SBBM5oUwYs9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}