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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7721b87343f435a2bcb17fea54dc2d081463b01ef48ac27480bb29d7a5b5a0b2' 
  AND token = 'u2ry9XlmUcaZYlGFSnRVH25Cqkstm8pwGG5aSo5b4+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}