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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '222c5a10c84aa4d4345bc2303622ddfac369ab22acc095a625ffa5976f5e871c' 
  AND token = 'PXL6lKIK8BTLv6TO1GOLjWX4U94rtbgGaFPBCcX9SCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}