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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '017d721cdd29266e5680c108dc776d69a0a16244c652f1e134570cec0edf39b3' 
  AND token = 'YMdonrMye3YkBpPa/FlwDmYEUmGD+nWGh81rgrs4f5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}