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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '37b87eeadeac8a70a76c765954aa9dac0a8329e63a708b23b2a8fa8638704188' 
  AND token = 'pWTA+6FCVsKKNE2/BPbnNCkD2DKSSQrAdeWUyT0NXCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}