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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '43af9bdd684f63b1d9185c49199a72fd3aa0c0c49e98255f70a5e78e352efaaa' 
  AND token = 'n0r0P7vW2E0m+LB4K8w6mIIz+Qif8LcsJ9KWcgeuJHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}