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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd04646d0ff584b262bd25c0879bb63014bc1cca02be20b868a8b405b0a54f600' 
  AND token = 'HhMvxu7MyRg7E6jUfcsHzNP9JMU3C3ewqgpBizrXbaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}