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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f983396e2caf5063455c7c6c546bbe321be6b26edaad63544ab5fa4c72a39d7e' 
  AND token = 'LoyQYMaqFQcF8ng054/SXmmZufaMPOQylZHcBoow9og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}