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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd343807a0bf52d14fbd28b675cf55971ca2726667567ed0db0573fc795fd95d7' 
  AND token = '7kgiwDLtaCmvZty5fiePAyz+VK/xMHGyf57TOyPeflQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}