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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e2a6f74381bf373151dc50e04a0d095e4477a9d88352e761f7f0acc66440f366' 
  AND token = 'RMg4WL7/iaBqUJloD+qIYm8R2L8cEWeJUV41TEp3Uiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}