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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '14b29b1b40104159da380fde59775014bc0af18fdd8265b5dd792e4129517021' 
  AND token = '80etHMfr5w1h+FaTDVF5XdekyAxCAeap+8L6XK1DUJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}