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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b42f9253d67e33eee9e067ca106e4bcc08d1457bc604d92adbe9f092ae245d12' 
  AND token = 'GSUPSIb276ulLtwS8ZxCFsQXKQOFC4NfJKxWZYmXSg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}