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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a398dcd25b00aece45618b8df215ddaced24ef77e4386dc538546377ffe4d337' 
  AND token = 'TEdUxS6BfstekRga8mB8a/axG/s7X/xeIV4k1H2r9Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}