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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8e98b7a298d4e91ae301112c399c67ad26987724f78ef33d7bf1ebc5b4f6a71f' 
  AND token = 'eRwcm4T+D/yg85YYwHeXuMze+Xyzed4r8PyttmiUC5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}