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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e144469cd7eefd17d44810a249e491be28595a7db17a03892b9e3fe8b0fedce3' 
  AND token = '24YlphCWbmz953J886eeMhEazVz1S9ATxBE4RMObksg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}