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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6ec9216c334514385a09a44ba3257c78a81047ce724bda98c880f4625b83dd09' 
  AND token = 'ZUbO8EE/fxeSPxFMR1gfbAkLwakSZPrKBaSVWNmjpBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}