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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '25376a5a9e344899119a996d5025853a91810eb0f2a0fcefa46111afb8baed40' 
  AND token = '8D57HUcitDvKepGFiGBdq2UZzLfalLMxMJ6y+vR+zc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}