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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9fdc145c31e6f9471006aaa00aa01e358bb725a72dc62a51e652e6c8e8cd46ce' 
  AND token = 'iLpwuLjlYlE7dHXhlbZ+MG19N1ehN+1446PZKMTk/6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}