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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cf6c6fd429d9d26a681212efb0308df0dc39f43dae020b97b27d69dd025ddbbc' 
  AND token = '50DBGBFPw6msUvP6IDylGhU0cba4wT63X9wqEVuDhaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}