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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1e13713ed36b7ce9751f256a0cf205accba906710fae64bfaa6af58bcaaf79c6' 
  AND token = '54fAdlBTmXWRDbcJWVvg2gyOOgbee1bAeB9ZsluKzrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}