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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '127e02b53e120f5278b7cee5c50068cfa1a721b53d93d58f1db996636b016062' 
  AND token = 'IjFNJyM+p/3Oc7NyGD6MYs9H+So7J8FwwaC5+8o4iwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}