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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '290c75b3f137c14dc565e20fb6fc9fc2a711ebb23e898cf84d50dd00ed7264a1' 
  AND token = 'M1xfTSidjz4EgXVRkxfSM4scuddA9F/IIiISzCjpURM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}