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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3a3856bad3d1042b4a029af3ade6fa2ec1f7a7f1af4244d35df264cd686c4a90' 
  AND token = 'r38nnIyz2qMbS6KgEIaotobDRii9MdFfSfaeBuAUzvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}