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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cffd49436e2d4d6f2735eca4b4c6d922075a7a9091da28af68b23ab3e3bb5324' 
  AND token = 'gQtm+SL/fTikGMVgs7HR+KRa9ZGYEc/ircdNoAkrCVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}