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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '46208c22c6748075f5a71dc38110090ea1b37dd5cac1b071000c6cef427bcda4' 
  AND token = 'U+S4BiD+xS88+foo8dC27vS4TPGOJX/LlVKsTfgKG68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}