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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e7125c7679a46c80f6d8a69ffe1f619aa878125fb5a5eea7a781fbe44919addc' 
  AND token = '45ARkPwKfbbdmIZQFCQVnj97985QGFqgDi2HfpKViC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}