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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4b49de05fc23cde4d65674d6d55f5fb8b31b125c669934fc92f8f7e23135a0a6' 
  AND token = 'y9+FeXTqizLdx/JnYQsA1MGe41ydObqrM+8ZTMb6d9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}