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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22a108ee80124cee339aee24b581537709b60340c24a92bb9c8220effb360654' 
  AND token = 'tJCoN4xTUgU7TaEjd/E8apSfhpCfXeryQokHcCvS59A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}