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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '37c4a66b45dfb215efb84848a03fb7a828b3cf1b38f1fab383d659b6feaeefde' 
  AND token = 'p3U5H2/0+2r5j+OyKi629kuUH2Xb44sw28ajUhQ5OSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}